Study Finds Growing Reason to Be Wary of Some Reflux Drugs

admin 20 Feb , 2017 0 comments

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If caught early, the condition can be treated and leave no signs of damage to your kidneys. It has not been proven that PPI use causes chronic kidney disease, but some studies suggest there is an increased risk of chronic kidney disease in individuals who have normal kidney function before using a PPI. This does not mean that everyone who uses PPIs will get chronic kidney disease, but it is important to know that there may be a risk. Studies did not include individuals who currently have kidney disease, so it is not clear if PPI use can make kidney disease worse. If a child or teen develops heartburn after eating, his or her doctor may prescribe an antacid and an H2 blocker.

Like most medications, there are side-effects and complications. Fortunately the overall risk of long-term PPI use still seems to be relatively small. There have been other reports over the past couple of years about the possible risk of pneumonia and infections of the colon with a bacterium called clostridium difficile in patients taking PPIs. Again, these articles looked at the medical records of hundreds of thousands of patients and found a small increased risk in patients using PPIs. Additionally, like the hip fracture study, other medical illness such as diabetes, heart and lung disease were also important risk factors.

A 2016 study in Circulation found PPIs increased stroke risk by 21 percent on average. But risk varied by the type of PPI and the dose. Researchers found Prilosec in 40 mg or higher doses increased the risk by 40 percent. A 2018 study looked at medical records of 796,000 patients.

It treats severe stomach acid-related conditions. It is not meant for treating occasional heartburn.

These medicines block production of stomach acid. These symptoms may mean you have acid reflux and heartburn, which can usually be relieved by antacids and no medical treatment. If symptoms become serious and happen more than once a week, it could mean you have gastroesophageal reflux disease (GERD).

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The difference is that GERD is a disease, and heartburn is its most common symptom. If you think you might have GERD, contact your doctor to discuss your symptoms. Prilosec and Zantac are medications used to treat digestive problems such as gastroesophageal reflux disease (GERD). They both work by reducing the amount of acid in your stomach, but Prilosec and Zantac do so in different ways.

Prilosec and Prilosec OTC are different in indication and dose form. Prilosec OTC is indicated for the treatment of frequent heartburn (heartburn that occurs two or more days per week). Prilosec is a prescription medication indicated for the treatment of many other acid-related conditions. However, the omeprazole active ingredient in Prilosec became available over-the-counter in 2003 in the form of Prilosec OTC. Omeprazole magnesium, the active ingredient in Prilosec OTC, is equivalent to the active ingredient in Prilosec to treat frequent heartburn.

Heartburn is a feeling of burning pain in your lower chest, behind the breastbone. It comes from acid backing up from your stomach to your throat. You may have seen ads for heartburn drugs, such as Nexium, Prilosec or Prevacid. These drugs are called PPIs (proton pump inhibitors). They keep the stomach from making too much acid.

Prilosec Dosage

Healthcare providers should follow up with people using omeprazole if their symptoms persist throughout treatment, or if their symptoms quickly return after stopping the medication. Omeprazole is a proton pump inhibitor (PPI).

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Prilosec is part of the class of drugs called proton pump inhibitors. It has an almost identical chemistry to Nexium (esomeprazole), another AstraZeneca PPI. Over-the-counter (OTC) medicines are drugs you can buy without a doctor’s prescription. There are 3 types of OTC medicines that treat heartburn and acid reflux. Better yet, nonpharmacological approaches can often reduce heartburn and other reflux-related problems.

Prilosec OTC is the over-the-counter version of Prilosec. It is probably the most familiar version of the medicine.

Researchers reviewed 874,000 children’s medical records. They zeroed in on those children given PPIs before their first birthday. The researchers found those children had a 22 percent greater risk for fractures.

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