Understanding Your Pathology Report: Esophagus With Reactive or Reflux Changes, Not Including Barrett’s Esophagus

admin 12 May , 2019 0 comments

Patients with laryngopharyngeal reflux present with symptoms related to the upper aerodigestive tract (Table 1) . The most common symptom reported by patients is a “lump in the throat” (globus sensation). Studies3- 5 have shown that in 23 to 60 percent of patients presenting with globus sensation, GERD is the etiologic factor. Gastroesophageal reflux is defined as the movement of gastric contents into the esophagus without vomiting.

These agents/factors include nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, cocaine, stress, radiation, bile reflux, and ischemia. The gastric mucosa exhibits hemorrhages, erosions, and ulcers.

You may feel fatigued and dizzy and look pale if you’re anemic. Gastritis usually affects your entire stomach, but sometimes it only affects the antrum – the lower part of the stomach. Gastritis can be short-term (acute) or long-term (chronic).

For several days afterward, barium liquid in the GI tract may cause white or light-colored stools. A health care provider will give the patient specific instructions about eating and drinking after the test. Upper GI endoscopy is a procedure that uses an endoscope-a small, flexible camera with a light-to see the upper GI tract. A health care provider performs the test at a hospital or an outpatient center. The health care provider carefully feeds the endoscope down the esophagus and into the stomach and duodenum.

When the damage to the mucosa is severe and long standing, the stomach loses its ability to produce acid. This may cause digestive upsets. The stomach has an internal lining, or mucous membrane, called the gastric mucosa. The mucosa must create hydrochloric acid to break down food, but also protect itself from the acidic contents that it creates. This delicate balance is controlled by three different glands in the lining of the stomach.

One study showed 25% of patients over 50 years old without GERD symptoms had Barrett’s esophagus. Barrett’s esophagus is a change in the lining of the esophagus from a normal, white lining (known as squamous mucosa) to a pink/red lining (known as intestinal-type mucosa). This change occurs over many years and is the esophageal response to chronic exposure to harmful chemicals from the stomach, most notably reflux of acid and bile. Fungal infections that cause gastritis include Candida albicans and histoplasmosis. Gastric phycomycosis is another rare lethal fungal infection.

Gastritis may be associated with other medical conditions, including HIV/AIDS, Crohn’s disease and parasitic infections. Autoimmune gastritis is more common in people with other autoimmune disorders, including Hashimoto’s disease and type 1 diabetes.

pylori. Chronic gastritis does not usually cause indigestion or pain, but severe damage may result in anemia due to vitamin B12 deficiency.

  • peptic ulcers.
  • They should interview the surgeon about his/her results.
  • not already receiving it.
  • [Medline].
  • This endoscopic image of eosinophilic esophagitis shows rings of abnormal tissue (esophageal rings) resulting from chronic inflammation.

What are the symptoms?

Treatment is supportive, with removal of the inciting cause and initiation of acid-suppressant therapy. Certain ICU patients (eg, ventilator-bound, head trauma, burn, multisystem trauma) benefit from prophylaxis with acid suppressants. I like to use a common sense approach when making dietary recommendations.

The two conditions have many symptoms in common, but an intense, localized pain is much more likely to occur with an ulcer. A peptic ulcer also carries a higher risk of bleeding and cancer, and it can lead to stomach perforation. Doctors use a variety of techniques to diagnose each of the conditions, which will require different methods of treatment. Antireflux surgery may be a consideration in patients with chronic symptoms that do not respond to adequate medical therapy. In one study10 of patients with GERD and laryngeal disease, 82 percent of the patients had resolution of laryngeal symptoms and normalization of laryngoscopic findings by six months or more after antireflux surgery.

Approximately 48 hours later, a laser is used to burn the photosensitized Barrett’s cells which are sensitive to the laser because of the photosensitizing agent. Normal tissue is not burned because it has not taken up the photosensitizing agent and is not sensitive to the laser. The dysplasia is eliminated in a majority of patients.

Damage to the stomach lining, which leads to reactive gastritis. Some people who have damage to the stomach lining can develop reactive gastritis. If an H. pylori infection is the cause of your gastritis, you’ll need to take a course of antibiotics alongside a proton pump inhibitor.

It can cause heartburn. The contents of the stomach contain acid, and when the esophagus is exposed to the acid over a long time it can injure its squamous lining. This causes certain changes that the pathologist can see under the microscope. Barrett’s esophagus does not have any specific symptoms, although patients with Barrett’s esophagus may have symptoms related to GERD.

H. pylori is a bacterium adapted to live in harsh, acidic environment that dwells in the stomach. It is linked to the development of stomach ulcers.

Written By admin

Leave a Reply

Your email address will not be published. Required fields are marked *